| Document |
Document Title |
|
JP2008001719A |
To provide methods for the prophylaxis, management and treatment of certain diseases modulated by the inhibition of the enzyme malonyl-coenzyme A decarboxylase (malonyl-CoA decarboxylase, MCD).The invention relates to methods for the pro...
|
|
JP2008001647A |
To solve the problems in the production of a Grignard reagent by using magnesium and an alkyl iodide compound having a proper boiling point.The invention relates to a method for the production of a Grignard reagent by using tetrahydropyr...
|
|
JP4031652B2 |
|
|
JP4027315B2 |
The invention relates to a method for determining the enantiomer ratio of trimethylcyclopentene derivatives of structure (I), wherein Z is an alkyl radical having 1-10 C atoms, can be saturated or olefinically unsaturated, straight-chain...
|
|
JP2007537171A |
The present invention concerns novel bidentante optionally N-containing P-ligands of general formula (I) embracing a two-ring-system and processes for synthesizing them, transition metal complexes of these compounds and their use as cata...
|
|
JP4021489B2 |
PCT No. PCT/GB97/01285 Sec. 371 Date Nov. 12, 1998 Sec. 102(e) Date Nov. 12, 1998 PCT Filed May 12, 1997 PCT Pub. No. WO97/43242 PCT Pub. Date Nov. 20, 1997A process for the production of at least one C4 compound selected from butane-1,4...
|
|
JP2007314576A |
To provide a method for synthesizing an objective organic molecule by using an organic/fluorous phase separation technique. The synthesizing method comprises the steps of: (a) reacting a first organic compound with a first fluorination-r...
|
|
JPWO2005042453A1 |
The present invention provides a fluorinated compound having functional groups in a high concentration so that adequate characteristics of the functional groups can be obtained and having high transparency in a wide wavelength region, a ...
|
|
JP2007534670A |
Process for preparing a propargyl alcohol of the formula I in which R1 is a C130-alkyl, C3-8-cycloalkyl, C2-20-alkoxyalkyl, C6-14-aryl, C7-20-alkoxyarl, C7-20-aralkyl, C7-20-alkylaryl radical or H, by reacting a corresponding aldehyde of...
|
|
JP4014102B2 |
To provide an efficient catalytic photo-oxygenation reaction of substrates by using water as the oxygen source. The catalytic photo-oxygenation reaction of substrates, using water as the oxygen source is provided by combining a reaction ...
|
|
JP4013444B2 |
|
|
JP2007533597A |
In the production of propargyl alcohol (I) by conversion of an aqueous formaldehyde solution containing acetylene in presence of a catalyst containing copper acetylide at 1-15 (preferably 3-7) bars and 70-120[deg]C without formation of a...
|
|
JP4011022B2 |
A novel polymer-supported arene-ruthenium complex represented by the following formula: , wherein A represents an organic polymer with a side chain containing an aromatic ring coordinated to Ru, X1 and X2 represent the same or different ...
|
|
JP2007297397A |
To provide a method for more industrially advantageously producing diols. A method is provided for producing diols represented by formula (4) (wherein R1, R2, R3, and R4are as defined below) which comprises reducing with a reducing agent...
|
|
JP2007297285A |
To provide a method for preparing an optically active hydroxy compound high in yield and optical purity. The method for preparing an optically active hydroxy compound represented by formula (4) (wherein R4is a hydrocarbon group or a hete...
|
|
JP4007579B2 |
|
|
JP2007290973A |
To obtain a nucleophilic reactant, in which a hydrocarbon group is added to a carbonyl carbon or an imino carbon, in high selectivity even under a mild condition. Benzophenone (3.35mmol) is stirred in THF in the presence of zinc chloride...
|
|
JP4004123B2 |
|
|
JP2007530248A |
Supported reactive catalysts having a controlled coordination structure and methods for their production are disclosed. The supported catalyst comprises catalyst particles having top or outer layer of atoms in which at least a portion of...
|
|
JP4002114B2 |
|
|
JP4001913B2 |
Novel trienoic retinoid compounds having activity for retinoic acid receptors and retinoid X receptors are provided. Also provided are pharmaceutical compositions incorporating such compounds and methods for their use.
|
|
JP3999030B2 |
The present invention relates to a fluorine-containing polymerizable monomer having a structure of the general formula (1), where each of R1 and R2 is independently a methyl group or trifluoromethyl group, and each of R3 and R4 is indepe...
|
|
JP3999028B2 |
|
|
JP4000820B2 |
|
|
JP2007275058A |
To provide a method for producing an optically active alcohol compound which is an important intermediate of a thrombopoietin receptor by bringing culture products and microbial cells or an enzyme existing therein into contact with an un...
|
|
JP2007277256A |
To provide an improved method for the [2+2+2] cyclotrimerization reaction in an aqueous solution using a water-soluble transition metal catalyst. The synthesizable compound is a substituted aromatic compound expressed by general formula ...
|
|
JP3993287B2 |
|
|
JP3989598B2 |
|
|
JP3984913B2 |
A process for the preparation of 4-methyl-2,3,5,6-tetrafluorobenzyl alcohol comprising hydrogenating 4-methyl-2,3,5,6-tetrafluorobenzonitrile to 4-methyl-2,3,5,6-tetrafluorobenzylamine and converting 4-methyl-2,3,5,6-tetrafluorobenzylami...
|
|
JP3987278B2 |
A process for the preparation of 1,4 butenediol comprising hydrogenating an aqueous solution of 1,4 butynediol under stirring conditions over a supported platinum or palladium and nickel catalyst in basic medium at a temperature in the r...
|
|
JP3982829B2 |
Osmium-catalyzed methods of addition to an olefin are discussed. In the method of asymmetric dihydroxylation of the present invention, an olefin, a chiral ligand, an organic solvent, an aqueous solution, a base, a ferricyanide salt and a...
|
|
JP2007238528A |
To manufacture a fluorine-containing allyl alcohol which is a useful intermediate for medicines and agrochemicals, by using 1-chloro-3,3,3-trifluoropropene as a raw material. The 1-chloro-3,3,3-trifluoropropene is added to 1.65 moles or ...
|
|
JP2007238480A |
To provide a method for stably preparing optically active alcohols with high optical purity, by establishing and standardizing a method for analyzing the purity of an industrially useful, optically active lactam alcohol derivative. The o...
|
|
JP2007238508A |
To provide a method for efficiently producing high purity geranyl geraniol which is a raw material of an intermediate for various useful materials, especially pharmaceuticals. The method for producing high purity geranyl geraniol is to r...
|
|
JP2007238527A |
To provide a method of manufacturing a fluorine-containing propargyl alcohol useful as a compound which can derive a fluorine-containing allyl alcohol or the like from 1-chloro-3,3,3-trifluoropropene as a raw material. The 1-chloro-3,3,3...
|
|
JP3976357B2 |
|
|
JP3976503B2 |
The invention provides a microencapsulated Lewis acid characterized in that a Lewis acid is supported through coordinate bonds on microcapsules formed of an organic polymer as a novel Lewis acid supported on a polymer in order to overcom...
|
|
JP2007230931A |
To provide a method for producing a 1,3-diyne compound under mild reaction condition, using an extremely small amount of expensive noble metal catalysts, without using a ligand and an oxidizing agent except for oxygen, and enabling easy ...
|
|
JP2007525496A |
Drugs that inhibit, antagonize, or short-circuit the visual cycle in steps of the visual cycle that occur beyond the disc of photoreceptor cells in the rodents are drugs for the treatment or prevention of ophthalmic diseases. May be used...
|
|
JP3965606B2 |
To easily produce the subject compound having high optical purity and useful as a synthetic raw material for pharmaceuticals by converting a racemic 2-halo-1-(substituted phenyl)ethanol into a phthalic acid ester and treating the product...
|
|
JP3963822B2 |
To provide a method for manufacturing an optical isomer separating agent having both of high optical resolution capacity and satisfactory solvent resistance. This method for manufacturing the optical isomer separating agent comprises a s...
|
|
JP3957346B2 |
To realize a method for producing an optically active alcohol useful as a synthetic intermediate for medicines, agrochemicals, etc., or as a raw material for liquid crystals, fine chemicals, etc., by using an easily handleable hydrid red...
|
|
JP2007197376A |
To provide a reagent capable of selectively reducing an aldehyde alone through discriminating the aldehyde and a ketone. A compound represented by the formula, NaBH(OCH(CF3)2)3, is provided. This compound is obtained by reaction between ...
|
|
JP3955257B2 |
To provide a new organic catalyst using a metallic component, highly easy to recover from a synthetic reaction product and reuse, or to provide a polymer-fixed organic substance useful as e.g. an intermediate for synthesis, and a catalys...
|
|
JPWO2005080300A1 |
An optical resolution agent composed of a bicyclo [3.3.0] -2-oxaoctane compound represented by the formulas [1] to [3], and a mixture of the optical resolution agent and an optically active substance having active hydrogen are reacted to...
|
|
JP2007186440A |
To provide a method for improving the hydrolysis reaction rate of chloromethyl groups and also improving the yield of a hydrolysis product.This method for hydrolyzing the chloromethyl groups bonding with an aromatic ring is provided by p...
|
|
JP2007519618A |
A compound of Formula (I): Formula (I) wherein: R1 is selected from hydrogen and C1-4alkyl; R2 is selected from: R4-C(R5aR5b)-, R4-C(R6)- and R7aC(R7b)-C(R6)-; R3X- is selected from methyl, methoxymethyl and; R4 is selected from (optiona...
|
|
JPWO2005051878A1 |
Providing a method for preserving formaldehyde under room temperature conditions and in a monomeric state. Provided is a method for hydroxyalkylating a nucleophile using a zeolite carrying aldehydes. The above-mentioned problems are solv...
|
|
JP2007516250A |
The present invention relates to a process for preparing tetrahydrogeranylacetone (tetrahydropseudoionone) by aldol condensation of citral with acetone and subsequent hydrogenation. The invention further relates to the use of thus obtain...
|
|
JP3930349B2 |
To provide a multifunctional reusable catalyst and a process for the preparation thereof on a single matrix of the support to perform multicomponent reaction in a single pot. The multifunctional catalysts which are useful for the synthes...
|
