Title:
【発明の名称】ファルネシル―タンパク質転移酵素の阻害剤
Document Type and Number:
Japanese Patent JP2000504017
Kind Code:
A
Abstract:
The present invention is directed to compounds which inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and the farnesylation of the oncogene protein Ras.
Inventors:
Danesmore, Christopher Jay
Heartman, Yogyi Day
Heartman, Yogyi Day
Application Number:
JP52785797A
Publication Date:
April 04, 2000
Filing Date:
January 27, 1997
Export Citation:
Assignee:
Merck End Company, Inc.
International Classes:
C07D233/64; A61K31/00; A61K31/415; A61K31/4164; A61P43/00; C07D231/12; C07D233/54; C07D233/60; C07D233/61; C07D233/66; C07D233/90; (IPC1-7): C07D233/64; A61P43/00; A61K31/4164
Attorney, Agent or Firm:
Yoshio Kawaguchi (2 outside)