Title:
【発明の名称】R-およびS-エナンチオマーの別の部分を含む製剤
Document Type and Number:
Japanese Patent JP2001514651
Kind Code:
A
Abstract:
A pharmaceutical dosage form comprises, in one portion thereof, a substantially single (+)-enantiomer of a chiral drug other than verapamil and, in another, separate portion thereof, a substantially single (-)-enantiomer of the drug wherein, in use, the different enantiomers are released at different rates from the dosage form. The dosage form is useful for administration of chiral drugs where both enantiomers have a valid pharmacological input, and where a clinical benefit may be realised by controlling the release rates of those enantiomers. Examples of such drugs include, in particular, tramadol and warfarin.
Inventors:
Gilbert, Julian Clive
Richards, Andrew John McGrashan
Bursley, Hazel Judith
Richards, Andrew John McGrashan
Bursley, Hazel Judith
Application Number:
JP53935798A
Publication Date:
September 11, 2001
Filing Date:
March 11, 1998
Export Citation:
Assignee:
DARWIN DISCOVERY LIMITED
International Classes:
A61K9/20; A61K9/24; A61K9/48; A61K9/50; A61K9/22; A61K9/52; A61K9/70; A61K31/135; A61K31/34; A61K31/365; A61K31/40; A61K31/445; A61K31/55; A61K; (IPC1-7): A61K9/22; A61K9/48; A61K9/70; A61K31/135
Attorney, Agent or Firm:
Aoyama Ryo (2 outside people)