Title:
【発明の名称】生物学的相互作用を調節する新規化合物についてのスクリーニング
Document Type and Number:
Japanese Patent JP2001520022
Kind Code:
A
Abstract:
Disclosed is a process for identifying compounds having a specified activity of interest, which process comprises (i) introducing interacting molecules into a host cell under conditions to generate or repress a detectable signal; and (ii) introducing a third compound or gene or genes encoding a third compound into the host cell from (i); and (iii) screening said host cell utilizing a method for detecting the inhibition or enhancement of interaction of proteins or other molecules in an in vivo or in vitro system. Another aspect of the present invention provides a process for identifying compounds of interest, which process comprises (i) generating one or more expression libraries derived from nucleic acid directly isolated from the environment; and (ii) screening said libraries utilizing a method for detecting the inhibition or enhancement of interaction of proteins or other molecules in an in vivo or in vitro system.
Inventors:
Short, Jay, M.
Application Number:
JP2000516069A
Publication Date:
October 30, 2001
Filing Date:
October 15, 1998
Export Citation:
Assignee:
Diversa corporation
International Classes:
G01N33/50; C12N15/09; C12N15/10; C12P7/26; C12Q1/02; C12Q1/26; C12Q1/34; C12Q1/48; C12Q1/68; C12Q1/6897; G01N33/15; G01N33/53; C12R1/01; (IPC1-7): C12Q1/68; C12N15/09; C12P7/26; G01N33/15; G01N33/50; G01N33/53
Attorney, Agent or Firm:
Yusuke Hiraki (1 person outside)