Title:
【発明の名称】β-グルコシダーゼの増強された産生のための遺伝子構築物および遺伝子改変された微生物
Document Type and Number:
Japanese Patent JP2002506616
Kind Code:
A
Abstract:
The present invention relates to increasing the production of a protein of interest from a fugal host. The invention discloses nucleotide sequences comprising, a regulatory region in operative association with xylanase secretion sequence and a gene of interest. The gene of interest encodes a protein selected from a pharmaceutical, nutraceutical, industrial, animal feed, food additive and an enzyme. Preferably, the gene of interest encodes a cellulase, hernicellulase, a lignin degrading enzyme, pectinase, protease, or peroxidase. The present invention also relates to vectors and hosts comprising these nucleic acid sequences, and to methods for the production of a protein of interest.
Inventors:
White, Celessa Sea.
Hindle, Christopher Dee.
Hindle, Christopher Dee.
Application Number:
JP2000535729A
Publication Date:
March 05, 2002
Filing Date:
March 09, 1999
Export Citation:
Assignee:
Iogen Corporation
International Classes:
C12N15/09; C12N1/15; C12N1/21; C12N9/24; C12N9/42; C12R1/885; (IPC1-7): C12N15/09; C12N1/15; C12N1/21; C12N9/42
Domestic Patent References:
| JPH06503960A | 1994-05-12 | |||
| JPH03280886A | 1991-12-11 | |||
| JPH04500313A | 1992-01-23 |
Other References:
APPL. MICROBIOL. BIOTECHNOL., vol. 45, JPN5001007176, 1996, pages 646 - 651, ISSN: 0000797486
APPL. MICROBIOL. BIOTECHNOL., vol. 45, JPN5001007177, 1996, pages 755 - 763, ISSN: 0000797487
APPL. MICROBIOL. BIOTECHNOL., vol. 45, JPNX007048083, 1996, pages 646 - 651, ISSN: 0000890716
APPL. MICROBIOL. BIOTECHNOL., vol. 45, JPNX007048084, 1996, pages 755 - 763, ISSN: 0000890717
APPL. MICROBIOL. BIOTECHNOL., vol. 45, JPN5001007177, 1996, pages 755 - 763, ISSN: 0000797487
APPL. MICROBIOL. BIOTECHNOL., vol. 45, JPNX007048083, 1996, pages 646 - 651, ISSN: 0000890716
APPL. MICROBIOL. BIOTECHNOL., vol. 45, JPNX007048084, 1996, pages 755 - 763, ISSN: 0000890717
Attorney, Agent or Firm:
Shusaku Yamamoto