Title:
【発明の名称】エポチロン生合成用遺伝子
Document Type and Number:
Japanese Patent JP2002518004
Kind Code:
A
Abstract:
Nucleic acid molecules are isolated from Sorangium cellulosum that encode polypeptides necessary for the biosynthesis of epothilone. Disclosed are methods for the production of epothilone in recombinant hosts transformed with the genes of the invention. In this manner, epothilone can be produced in quantities large enough to enable their purification and use in pharmaceutical formulations such as those for the treatment of cancer.
More Like This:
Inventors:
Thomas Sup
James Madison Lygon
Istvan Molnar
Ross Zakur
Jane Gerach
Devon sia
James Madison Lygon
Istvan Molnar
Ross Zakur
Jane Gerach
Devon sia
Application Number:
JP2000554837A
Publication Date:
June 25, 2002
Filing Date:
June 16, 1999
Export Citation:
Assignee:
Novartis Actien Gezel Shaft
International Classes:
C07K14/195; C12N1/21; C12N9/00; C12P7/00; C12P17/18; C12N15/09; C12R1/01; C12R1/465; (IPC1-7): C12N15/09; C12N1/21; C12N9/00; C12P7/00
Attorney, Agent or Firm:
Aoyama Ryo (2 outside people)