【発明の名称】マウスセロトニン5-HT2cレセプターのアイソフォーム

Title:

【発明の名称】マウスセロトニン5-HT2cレセプターのアイソフォーム

Document Type and Number:

Japanese Patent JP2002539774

Kind Code:

A

Abstract:

The invention includes mouse serotonin 5-HT2c receptor isoforms having amino acid replacements at one or more positions of the natural mouse serotonin 5-HT2c receptor polypeptide sequence, specifically at one or more of positions 157, 159 and 161. The polypeptides are useful for identifying ligands which bind with the serotonin 5-HT2c receptor and modulators of the serotonin 5-HT2c, and for identifying drugs with affinity for 5-HT2 receptors which are used to treat schizophrenia, Parkinsonism, and anxiety disorders.

More Like This:

JP4445703	Cytomegalovirus Intron A Fragment
JP2010136660	METHOD FOR INSPECTING IRREGULAR PULSE BY DETECTING VARIANT OF POTASSIUM CHANNEL CONTROLLING G PROTEIN, AND IRREGULAR PULSE-AMELIORATING AGENT
JP5125082	Base mutation detection method and base mutation detection system

Inventors:

Huong, Toun M
Liu, Jie
Juan del Proof, Leonardus Her Te

Application Number:

JP2000605631A

Publication Date:

November 26, 2002

Filing Date:

March 10, 2000

Export Citation:

Click for automatic bibliography generation Help

Assignee:

Merck End-Campany Inc.

International Classes:

C12N15/09; C07K14/705; C07K14/715; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/12; C12Q1/02; C12Q1/68; A61K38/00; (IPC1-7): C12N15/09; C07K14/715; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12Q1/02

Attorney, Agent or Firm:

Yoshio Kawaguchi (5 outside)

Previous Patent: 分泌タンパク質およびそれらをコードする核酸

Next Patent: ５０個のヒト分泌タンパク質