Title:
【発明の名称】ヘムオキシゲナーゼ活性の調節による移植片の生存を強化する方法
Document Type and Number:
Japanese Patent JP2003500335
Kind Code:
A
Abstract:
Methods are provided wherein the survival of an organ transplant is enhanced by introducing into cells of the transplant a nucleic acid molecule that modulates heme oxygenase-I activity therein. Nucleic acid molecules that modulate heme oxygenase-I activity and therefore find use in the described methods include, for example, molecules that encode a polypeptide that itself exhibits heme oxygenase-I activity or antisense oligonucleotides that act to inhibit heme oxygenase-I activity in a cell.
Inventors:
Bureau roland
Woo Jackie
Ayer Susini
Woo Jackie
Ayer Susini
Application Number:
JP2000588362A
Publication Date:
January 07, 2003
Filing Date:
December 17, 1999
Export Citation:
Assignee:
Sangustat Medical Corporation
International Classes:
A61K9/127; A61K31/7088; A61P37/06; A61P43/00; C12N5/02; C12N15/09; C12N9/02; C12N15/53; A61K48/00; (IPC1-7): A61K31/7088; A61K9/127; A61P37/06; A61P43/00; C12N15/09
Attorney, Agent or Firm:
Minoru Nakamura (9 outside)