Title:
【発明の名称】カスパーゼ3発現のアンチセンスモジュレーション
Document Type and Number:
Japanese Patent JP2003520584
Kind Code:
A
Abstract:
Antisense compounds, compositions and methods are provided for modulating the expression of caspase 3. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding caspase 3. Methods of using these compounds for modulation of caspase 3 expression and for treatment of diseases associated with expression of caspase 3 are provided.
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Inventors:
Jean, Hong
Kausart, Rex M
Kausart, Rex M
Application Number:
JP2001553784A
Publication Date:
July 08, 2003
Filing Date:
January 11, 2001
Export Citation:
Assignee:
Isis PharmaceuticalsInc
International Classes:
C12N15/09; A61K9/107; A61K31/7115; A61K31/712; A61K31/7125; A61K48/00; A61P1/16; A61P7/06; A61P9/10; A61P37/02; A61P43/00; C12N15/113; A61K38/00; (IPC1-7): C12N15/09; A61K9/107; A61K31/7115; A61K31/712; A61K31/7125; A61K48/00; A61P1/16; A61P7/06; A61P9/10; A61P37/02; A61P43/00
Attorney, Agent or Firm:
Kazuo Shamoto (5 outside)