Title:
【発明の名称】オピオイドおよびそのアンタゴニストに関する新規方法および組成物
Document Type and Number:
Japanese Patent JP2003528819
Kind Code:
A
Abstract:
Novel methods and compositions comprising opioids and opioid antagonists. In preferred embodiments, the methods and compositions comprise opioids and peripheral mu opioid antagonist compounds. The methods and compositions are particularly suitable for treating and/or preventing side effects associated with opioids including, for example, constipation, vomiting and/or nausea. Figures 2A aand 2B are graphical representations of studies on the inhibition of nausea and vomiting employing methods according to an embodiment of the present invention,
More Like This:
Inventors:
Farrer, John Jay
Application Number:
JP2001539402A
Publication Date:
September 30, 2003
Filing Date:
November 29, 2000
Export Citation:
Assignee:
Adler Corporation
International Classes:
A61K45/00; A61K31/439; A61K31/445; A61K31/451; A61K31/4748; A61K31/485; A61P1/00; A61P25/02; A61P43/00; (IPC1-7): A61K31/451; A61K31/439; A61K31/485; A61K45/00; A61P1/00; A61P25/02; A61P43/00
Foreign References:
| US4582835A | 1986-04-15 | |||
| US4457933A | 1984-07-03 | |||
| US4769372A | 1988-09-06 | |||
| EP0287339A2 | 1988-10-19 | |||
| US5250542A | 1993-10-05 |
Attorney, Agent or Firm:
Kazuo Shamoto (5 outside)