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Title:
T細胞亜集団に特異的なモノクローナル抗体およびポリクローナル抗体の組成物および使用方法
Document Type and Number:
Japanese Patent JP2004501165
Kind Code:
A
Abstract:
The invention provides compounds and methods for the ex vivo or in vivo< expansion of NK T cells, CD1d-reactive T cells, and J alpha Q<+> cells, and the modulation of their activities. These compounds and methods have diagnostic and therapeutic applications.

Inventors:
Exley Mark A.
Wisleson Samuel Bee.
Bork Stephen Pee.
Application Number:
JP2002504312A
Publication Date:
January 15, 2004
Filing Date:
June 19, 2001
Export Citation:
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Assignee:
Beth Israel Deaconess Medical Center
Dana-Farber Cancer Institute, Inc.
International Classes:
G01N33/53; A61K39/395; A61K47/48; A61P11/06; A61P15/00; A61P15/04; A61P15/06; A61P29/00; A61P31/00; A61P31/04; A61P31/12; A61P33/00; A61P35/00; A61P37/00; A61P37/02; A61P37/04; A61P37/06; A61P37/08; A61P43/00; C07K16/28; C12N5/0783; C12N5/10; C12N5/20; A61K35/12; A61K39/00; (IPC1-7): C07K16/28; A61K39/395; A61K47/48; A61P11/06; A61P15/04; A61P15/06; A61P29/00; A61P31/04; A61P31/12; A61P33/00; A61P35/00; A61P37/02; A61P37/04; A61P37/06; A61P37/08; A61P43/00; C12N5/06; C12N5/10; G01N33/53
Foreign References:
WO1999034209A11999-07-08
WO1999034209A11999-07-08
Other References:
JPN5003002143; WILSON S BRIAN: DIABETES V50NSUPPLEMENT2, 200106, PA267
JPN6011013366; J.exp.Med. Vol.188, 1998
JPN6011013367; Immunology Vol.99, 2000, p.229-234
JPN6011013368; Annual review 免疫 , 1998, p.176-187
JPN6011013369; Annual review 免疫 , 1999, p.88-97
JPN6011013366; J.exp.Med. Vol.188, 1998
JPN6011013367; Immunology Vol.99, 2000, p.229-234
JPN6011013368; Annual review 免疫 , 1998, p.176-187
JPN6011013369; Annual review 免疫 , 1999, p.88-97
JPN5003002143; WILSON S BRIAN: DIABETES V50NSUPPLEMENT2, 200106, PA267
Attorney, Agent or Firm:
Hatsushi Shimizu
Kazunori Hashimoto