ナトリウムチャネルブロッカーの結合物及びその使用法 - The University of North Carolina at Chapel Hill

Title:

ナトリウムチャネルブロッカーの結合物及びその使用法

Document Type and Number:

Japanese Patent JP2004513870

Kind Code:

A

Abstract:

Compounds of the general formula P1-L-P2; wherein "P1" is a pyrazinoylguanidine sodium channel blocker, "L" is a linking group, and "P2" is either (i) a pyrazinoylguanidine sodium channel blocker or (ii) a P2Y2 receptor agonist, are disclosed. Pharmaceutical formulations containing the same and methods of use thereof to hydrate mucosal surfaces such as airway mucosal surfaces are also disclosed.

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Inventors:

Voucher, richard sea, junior

Application Number:

JP2001511434A

Publication Date:

May 13, 2004

Filing Date:

July 19, 2000

Export Citation:

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Assignee:

The University of North Carolina at Chapel Hill
Voucher, richard sea, junior

International Classes:

C07D241/32; A61K31/495; A61K31/4965; A61K31/70; A61P1/04; A61P11/00; A61P11/12; A61P43/00; C07D241/26; C07D401/12; C07H19/10; C07H19/207; A61K; A61P; C07D; C07H; (IPC1-7): C07D241/32; A61K31/4965; A61P1/04; A61P11/00; A61P43/00

Attorney, Agent or Firm:

Shoichi Okuyama
Arihara Koichi
Matsushima Tetsuo

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