Title:
ヒト胚性幹細胞のトランスフェクション
Document Type and Number:
Japanese Patent JP2004520046
Kind Code:
A
Abstract:
Methods are provided for altering gene expression in a population of human embryonic cells that include introducing a gene expression altering sequence into cells the cells retaining their pluripotent character, for purifying pluripotent embryonic stem cells from a heterogeneous population of cells, and for treating a human suffering from a deficiency of a selected cell type. Reagent cell populations are further provided for supplying material for transplantation consisting essentially of pluripotent human embryonic stem cells modified by foreign genetic material.
Inventors:
Benvenist Nissim
Yanuca Ofura
Surdiner Maya
Aiges-Avenel Raquel
Yanuca Ofura
Surdiner Maya
Aiges-Avenel Raquel
Application Number:
JP2002561590A
Publication Date:
July 08, 2004
Filing Date:
November 27, 2001
Export Citation:
Assignee:
Ism Research Development Company of the Hebrew University of Jerusalem
International Classes:
C12N15/09; A61K35/12; A61K35/28; A61K35/30; A61K35/32; A61K35/34; A61K35/36; A61K35/44; A61P25/28; A61P35/00; A61P37/00; A61P37/02; C12N5/0735; C12N5/10; C12N15/87; C12Q1/02; A61K48/00; (IPC1-7): C12N15/09; A61K35/12; A61K35/28; A61K35/30; A61K35/32; A61K35/34; A61K35/36; A61K35/44; A61P25/28; A61P35/00; A61P37/00; A61P37/02; C12N5/10; C12Q1/02
Attorney, Agent or Firm:
Keiki Tanabe