Title:
リポペプチド抗生物質の抽出的精製
Document Type and Number:
Japanese Patent JP2004522733
Kind Code:
A
Abstract:
The present invention provides a rapid and inexpensive method for extractively isolating acidic lipopeptide antibiotics, such as those having a cyclic peptide or cyclic depsipeptide core, in high yield and purity. In particular, there is provided a method of extracting a variety of acidic lipopeptide antibiotics, directly or indirectly, into water immiscible organic solvents by using a divalent cation chelation procedure.
Inventors:
Borders, Donald Bee.
Francis, Noreen Dee.
Fantini, Amedeo Ae.
Francis, Noreen Dee.
Fantini, Amedeo Ae.
Application Number:
JP2002556605A
Publication Date:
July 29, 2004
Filing Date:
January 10, 2002
Export Citation:
Assignee:
Micrologix Biotech,Inc
International Classes:
C12P1/04; A01N37/46; B01D11/04; C07K1/14; C07K7/08; C07K7/56; C07K9/00; C07K11/02; A61K38/00; (IPC1-7): C07K1/14; A01N37/46; B01D11/04; C12P1/04
Attorney, Agent or Firm:
Hidesaku Yamamoto