Title:
核酸誘導体
Document Type and Number:
Japanese Patent JP2004537503
Kind Code:
A
Abstract:
A compound which comprises a backbone having a plurality of chiral carbon atoms, the backbone bearing a plurality of ligands each being individually bound to a chiral carbon atom of the plurality of chiral carbon atoms, the ligands including one or more pair(s) of adjacent ligands each containing a moiety selected from the group consisting of a naturally occurring nucleobase and a nucleobase binding group, wherein moieties of the one or more pair(s) are directly linked to one another via a linker chain; building blocks for synthesizing the compound; and uses of the compound, particularly in antisense therapy.
Inventors:
David Segev
Application Number:
JP2002561045A
Publication Date:
December 16, 2004
Filing Date:
January 29, 2002
Export Citation:
Assignee:
Bio-Rad Laboratories, Inc.
International Classes:
C12N15/09; A61K31/439; A61K31/506; A61K31/513; A61K31/52; A61K31/675; A61K48/00; A61P1/04; A61P1/18; A61P7/00; A61P9/00; A61P9/10; A61P11/00; A61P11/06; A61P13/12; A61P17/00; A61P17/06; A61P17/12; A61P19/02; A61P27/02; A61P29/00; A61P31/10; A61P31/12; A61P31/16; A61P31/18; A61P31/22; A61P35/00; A61P37/04; C07D239/52; C07D498/18; C07H21/04; C12Q1/68; C12Q1/6832; C12Q1/6839; (IPC1-7): C07D239/52; A61K31/439; A61K31/513; A61K48/00; A61P1/04; A61P1/18; A61P7/00; A61P9/00; A61P9/10; A61P11/00; A61P11/06; A61P13/12; A61P17/00; A61P17/06; A61P17/12; A61P19/02; A61P27/02; A61P29/00; A61P31/10; A61P31/12; A61P31/16; A61P31/18; A61P31/22; A61P35/00; A61P37/04; C07D498/18; C12N15/09
Domestic Patent References:
| JPH10257888A | 1998-09-29 | |||
| JPH10509048A | 1998-09-08 | |||
| JPS62502338A | 1987-09-10 | |||
| JPS62502357A | 1987-09-10 |
Other References:
JPN6009010919, Ｂｉｏｍｅｄ． Ｅｎｖｉｒｏｎ． Ｍａｓｓ Ｓｐｅｃｔｒｏｍ．, 1989, Ｖｏｌ．１８， Ｎｏ．８, ５４７−５５２
Attorney, Agent or Firm:
Nobuaki Kazehaya
Noriko Asano
Noriko Asano