Title:
CCR1受容体アンタゴニスト活性を有するピペラジン誘導体
Document Type and Number:
Japanese Patent JP2005507923
Kind Code:
A
Abstract:
The present invention relates to compounds of the formula I and the pharmaceutically acceptable forms thereof; wherein X, Y, a, b, c, d, R1, R2, R3, R4 and R5 are as defined herein. Moreover, the present invention is also directed at pharmaceutical compositions comprising a compound of the formula I and a pharmaceutically acceptable carrier. Furthermore, the present invention is directed at methods of using the herein described compounds and compositions for treating or preventing a disorder or condition that can be treated or prevented by antagonizing the CCR1 receptor in a mammal.
Inventors:
Laura Cook Bloomberg
Matthew Frank Brown
Matthew Merrill Hayward
Christopher Stanley Post
Gregory Dean Lundkwist Jr.
Andrey Shavnya
Matthew Frank Brown
Matthew Merrill Hayward
Christopher Stanley Post
Gregory Dean Lundkwist Jr.
Andrey Shavnya
Application Number:
JP2003538143A
Publication Date:
March 24, 2005
Filing Date:
September 26, 2002
Export Citation:
Assignee:
Pfizer Products Inc.
International Classes:
A61K31/495; A61K31/496; A61P9/10; A61P11/00; A61P29/00; A61P31/18; A61P35/00; A61P37/06; A61P37/08; A61P43/00; C07D207/16; C07D213/63; C07D213/64; C07D213/74; C07D213/75; C07D213/76; C07D213/79; C07D241/04; C07D213/80; C07D213/82; C07D239/34; C07D239/60; C07D257/04; C07D277/56; C07D295/185; C07D307/33; C07D307/68; C07D333/38; C07D401/06; C07D401/10; C07D401/12; C07D403/10; C07D405/10; C07D409/10; C07D417/10; (IPC1-7): C07D241/04; A61K31/495; A61K31/496; A61P9/10; A61P11/00; A61P29/00; A61P31/18; A61P35/00; A61P37/06; A61P37/08; A61P43/00; C07D401/06; C07D401/10; C07D403/10; C07D405/10; C07D409/10; C07D417/10
Attorney, Agent or Firm:
Chika Takagi
Junji Yuda
Shoji Miwa
Junji Yuda
Shoji Miwa