Title:
PTP阻害剤としてのβ-カルボリン誘導体
Document Type and Number:
Japanese Patent JP2005508968
Kind Code:
A
Abstract:
This invention provides compounds which are useful as inhibitors of protein tyrosine phosphatases (PTPases). As inhibitors of PTPases, the compounds of the invention are useful for the management, treatment, control and adjunct treatment of diseases mediated by PTPase activity. Such diseases include type I diabetes, type II diabetes, immune dysfunction, AIDS, autoimmunity, glucose intolerance, obesity, cancer, psoriasis, allergic diseases, infectious diseases, inflammatory diseases, diseases involving the modulated synthesis of growth hormone or the modulated synthesis of growth factors or cytokines which affect the production of growth hormone, or Alzheimer's disease.
Inventors:
Mujari, Adnan Em. Em.
Andrews, Robert Sea.
Che, Longuan
Yalagunta, Ravindra Earl.
Ren, Tan
Andrews, Robert Sea.
Che, Longuan
Yalagunta, Ravindra Earl.
Ren, Tan
Application Number:
JP2003536235A
Publication Date:
April 07, 2005
Filing Date:
October 18, 2002
Export Citation:
Assignee:
TRANSTECH PHARMA,INC.
International Classes:
A61K31/437; A61K31/573; A61K31/64; A61K38/28; A61K45/00; A61P3/00; A61P3/04; A61P3/08; A61P3/10; A61P5/10; A61P17/06; A61P25/28; A61P29/00; A61P31/00; A61P31/04; A61P31/18; A61P35/00; A61P37/04; A61P37/06; A61P37/08; A61P43/00; C07D471/04; (IPC1-7): C07D471/04; A61K31/437; A61K31/573; A61K31/64; A61K38/28; A61K45/00; A61P3/04; A61P3/08; A61P3/10; A61P5/10; A61P17/06; A61P25/28; A61P29/00; A61P31/04; A61P31/18; A61P35/00; A61P37/04; A61P37/06; A61P37/08; A61P43/00
Attorney, Agent or Firm:
Hidekazu Miyoshi