Title:
抗糖尿病性の2-置換-5’-O-(1-ボラノトリホスフェート)アデノシン誘導体
Document Type and Number:
Japanese Patent JP2005508970
Kind Code:
A
Abstract:
2-Substituted-5'-O-(1-boranotriphosphate)adenosine derivatives having at position 2 a radical R1 selected from the group consisting of H; halogen; O-hydrocarbyl; S-hydrocarbyl; NR3R4; and hydrocarbyl optionally substituted by halogen, CN, SCN, NO2, OR3, SR3 or NR3R4; wherein R3 and R4 are each independently H or hydrocarbyl or R3 and R4 together with the nitrogen atom to which they are attached form a saturated or unsaturated heterocyclic ring optionally containing 1-2 further heteroatoms selected from oxygen, nitrogen and sulfur, and pharmaceutically acceptable salts or diastereoisomers thereof or a mixture of diastereoisomers, are useful for treatment of type 2 diabetes.
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Inventors:
Fisher Bilha
Clayman-Naham Victoria
Pettit pierre
Clayman-Naham Victoria
Pettit pierre
Application Number:
JP2003537547A
Publication Date:
April 07, 2005
Filing Date:
October 23, 2002
Export Citation:
Assignee:
Buryran University
University of Montpellier Eye
University of Montpellier Eye
International Classes:
A61K31/7076; A61P3/10; A61P43/00; C07H19/20; (IPC1-7): C07H19/20; A61K31/7076; A61P3/10; A61P43/00
Attorney, Agent or Firm:
Hatsushi Shimizu
Kazunori Hashimoto
Koichi Niimi
Kazunori Hashimoto
Koichi Niimi