Title:
HIVアスパルチルプロテアーゼ阻害剤としての尿素誘導体
Document Type and Number:
Japanese Patent JP2005519109
Kind Code:
A
Abstract:
The present invention provides HIV aspartyl protease inhibitors of the formula I: and when the compound of formula I comprises an amino group, pharmaceutically acceptable ammonium salts thereof, wherein n is 3 or 4, Y is O, S, NH or N-CN, wherein Cx may be, for example COOH, or CH20H, wherein R1 is selected from the group consisting of a benzenesulfonyl group of formula II as defined herein, wherein R2 may be, for example, iso-butyl, or 3-methylbutyl, and wherein R3 and R4 areas defined herein.
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Inventors:
Brent Richard Stranix
Abderahim Bourjid
Jill Sovet
Abderahim Bourjid
Jill Sovet
Application Number:
JP2003572939A
Publication Date:
June 30, 2005
Filing Date:
February 25, 2003
Export Citation:
Assignee:
Procion Biopharma Inc.
International Classes:
C07D295/12; A61K31/198; A61K31/357; A61K31/36; A61K31/381; A61K31/4045; A61K31/405; A61K31/4402; A61K31/4406; A61K31/4409; A61K31/4453; A61K31/472; A61P31/12; A61P31/18; A61P43/00; C07C311/06; C07C311/19; C07C311/42; C07C335/12; C07C335/14; C07D209/16; C07D209/20; C07D213/40; C07D213/81; C07D213/86; C07D217/12; C07D217/22; C07D317/58; C07D319/18; C07D333/20; C07D405/12; C07D409/12; (IPC1-7): C07C311/06; A61K31/198; A61K31/357; A61K31/36; A61K31/381; A61K31/4045; A61K31/405; A61K31/4402; A61K31/4406; A61K31/4409; A61K31/4453; A61K31/472; A61P31/12; A61P31/18; A61P43/00; C07D209/16; C07D209/20; C07D213/40; C07D213/86; C07D217/22; C07D295/12; C07D317/58; C07D319/18; C07D333/20; C07D405/12; C07D409/12
Attorney, Agent or Firm:
Masatake Shiga
Takashi Watanabe
Masakazu Aoyama
Yasuhiko Murayama
Shinya Mitsuhiro
Takashi Watanabe
Masakazu Aoyama
Yasuhiko Murayama
Shinya Mitsuhiro