Title:
イソキノリン誘導体
Document Type and Number:
Japanese Patent JP2005525363
Kind Code:
A
Abstract:
Isoquinoline derivatives of the general formula (I) in which X, Y, Z, R1, R2, and n are as defined in Patent Claim ( 1 ), and physiologically acceptable salts or solvates thereof, are integrin inhibitors and can be employed for combating thromboses, cardiac infarction, coronary heart diseases, arteriosclerosis, inflammation, tumours, osteoporosis, infections and restenosis after angioplasty or in pathological processes which are maintained or propagated by angiogenesis.
Inventors:
Wiesner, Matthias
Gutman, Gimon
Kessler, Horst
Tsum Sharn, Georgette
Webber, Dirk
Gott Shrink, Dirk
Gutman, Gimon
Kessler, Horst
Tsum Sharn, Georgette
Webber, Dirk
Gott Shrink, Dirk
Application Number:
JP2003572980A
Publication Date:
August 25, 2005
Filing Date:
February 07, 2003
Export Citation:
Assignee:
Merck Patent Gesellschaft mit beschraenkter Haftung
International Classes:
A61K31/472; A61K31/4725; A61K31/506; A61P7/02; A61P9/00; A61P9/10; A61P19/10; A61P29/00; A61P31/00; A61P35/00; A61P35/04; A61P43/00; C07D217/16; C07D401/12; (IPC1-7): C07D217/16; A61K31/472; A61K31/4725; A61K31/506; A61P7/02; A61P9/00; A61P9/10; A61P19/10; A61P29/00; A61P31/00; A61P35/00; A61P43/00; C07D401/12
Attorney, Agent or Firm:
Akio Miyazaki
Katsuhiro Ito
Ishibashi Masayuki
Katsuhiro Ito
Ishibashi Masayuki