壊死の治療および予防のための組成物および方法

Title:

壊死の治療および予防のための組成物および方法

Document Type and Number:

Japanese Patent JP2005526779

Kind Code:

A

Abstract:

A method for treating and/or preventing cell necrosis and diseases associated therewith, comprising the inhibition of one or more elastase enzymes within said cells.

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Inventors:

Nathan, Ilana
Liechtenstein, Alexandra

Application Number:

JP2003577802A

Publication Date:

September 08, 2005

Filing Date:

March 26, 2003

Export Citation:

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Assignee:

Ben-Gurion University of the Negev
Mole Research Applications Limited

International Classes:

A61K45/00; A61K8/64; A61K31/00; A61K38/07; A61K38/55; A61K45/06; A61P1/04; A61P1/16; A61P1/18; A61P3/10; A61P9/10; A61P11/00; A61P13/12; A61P15/00; A61P17/02; A61P17/06; A61P19/02; A61P21/04; A61P25/00; A61P25/28; A61P25/32; A61P25/36; A61P29/00; A61P31/04; A61P31/06; A61P31/12; A61P35/02; A61Q19/08; (IPC1-7): A61K45/00; A61K45/06; A61P1/04; A61P1/16; A61P1/18; A61P3/10; A61P9/10; A61P11/00; A61P13/12; A61P15/00; A61P17/02; A61P17/06; A61P19/02; A61P21/04; A61P25/00; A61P25/28; A61P25/32; A61P25/36; A61P29/00; A61P31/04; A61P31/06; A61P31/12; A61P35/02

Domestic Patent References:

JPS63152328A	1988-06-24
JPH04297446A	1992-10-21
JPH0578298A	1993-03-30

Foreign References:

WO2001026685A1	2001-04-19
WO2001023361A1	2001-04-05
WO1998039437A1	1998-09-11
WO2001058448A1	2001-08-16
WO2000041705A1	2000-07-20

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JPN6010000331; ＳＴＥＩＮ，Ｒ．Ｌ．　ｅｔ　ａｌ: 'Ｍｅｃｈａｎｉｓｍ　ｏｆ　ｉｎａｃｔｉｖａｔｉｏｎ　ｏｆ　ｈｕｍａｎ　ｌｅｕｋｏｃｙｔｅ　ｅｌａｓｔａｓｅ　ｂｙ　ａ　ｃｈｌｏｒｏｍｅｔｈｙｌ　ｋｅｔｏｎｅ：　ｋｉｎｅｔｉｃ　ａｎｄ　ｓｏｌｖｅｎｔ' ＢｉｏｃｈｅｍｉｓｔｒｙＶｏｌ．２５，　Ｎｏ．１９, 1986, ｐ．５４１４-９
JPN6010000335; 'Ｓｙｎｔｈｅｔｉｃ　ｉｎｈｉｂｉｔｏｒｓ　ｏｆ　ｈｕｍａｎ　ｎｅｕｔｒｏｐｈｉｌ　ｅｌａｓｔａｓｅ' Ｔｒｅｎｄｓ　ｉｎ　Ｐｈａｒｍａｃｏｌｏｇｉｃａｌ　ＳｃｉｅｎｃｅｓＶｏｌｕｍｅ　８，　Ｉｓｓｕｅ　８, 1987, Ｐａｇｅｓ　３０３-３０７
JPN6010000337; ＰＡＴＴＯＮ，Ｌ．Ｍ．: 'Ｉｎ　ｖｉｖｏ　ｅｖａｌｕａｔｉｏｎ　ｏｆ　ＭＤＬ　２０１，４０４ＹＡ，　ａ　ｎｏｖｅｌ　ｉｎｈｉｂｉｔｏｒ　ｏｆ　ｈｕｍａｎ　ｎｅｕｔｒｏｐｈｉｌ　ｅｌａｓｔａｓｅ' Ａｇｅｎｔｓ　Ａｃｔｉｏｎｓ　ＳｕｐｐｌＶｏｌ．４２, 1993, ｐ．８３-９６
JPN6010059112; ＢｉｏｃｈｅｍｉｓｔｒｙＶｏｌ．２５，　Ｎｏ．１９，, 1986, ｐ．５４１４-９
JPN6010059113; Ｔｒｅｎｄｓ　ｉｎ　Ｐｈａｒｍａｃｏｌｏｇｉｃａｌ　ＳｃｉｅｎｃｅｓＶｏｌｕｍｅ　８，　Ｉｓｓｕｅ　８, 1987, Ｐａｇｅｓ　３０３-３０７
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JPN6010059121; 兵庫県医師会医学雑誌第４２巻第３号, 2000, 第３３-３７頁
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JPN6012068327; Ｐａｎｃｒｅａｓ２１（４）, 200011, ４７４
JPN6012068333; 食品と開発３７（１）, 20020101, ６０-６５

Attorney, Agent or Firm:

Yusuke Hiraki
Ishii Teiji
Satoshi Fujita

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