Title:
腫瘍壊死因子産生の阻害剤としての1-チア-3-アザ-ジベンゾアズレン類及びその製造用中間体
Document Type and Number:
Japanese Patent JP2005529157
Kind Code:
A
Abstract:
The present invention relates to derivatives of 1-thia-3-aza-dibenzoazulene class, to their pharmacologically acceptable salts and solvates, to processes and intermediates for the preparation thereof as well as to their antiinflammatory effects, especially to the inhibition of tumour necrosis factor-alpha (TNF-alpha) production and the inhibition of interleukin-1 (IL-1) production as well as to their analgetic action.
Inventors:
Mersep, Muraden
Methic, Milan
Marina, Modric
Pesic, dyana
Kidmet, Dabol
Methic, Milan
Marina, Modric
Pesic, dyana
Kidmet, Dabol
Application Number:
JP2004507484A
Publication Date:
September 29, 2005
Filing Date:
May 20, 2003
Export Citation:
Assignee:
PRIVA-Istra Tsv Atsky Institute Day Oh Oh
International Classes:
A61K31/428; A61K31/43; A61K31/55; A61P1/04; A61P3/10; A61P9/02; A61P11/00; A61P11/06; A61P13/12; A61P17/00; A61P17/06; A61P25/28; A61P27/02; A61P29/00; A61P29/02; A61P35/00; A61P43/00; C07D513/02; C07D513/04; C07D417/04; (IPC1-7): C07D417/04; A61K31/428; A61K31/43; A61K31/55; A61P1/04; A61P3/10; A61P9/02; A61P11/00; A61P11/06; A61P13/12; A61P17/00; A61P17/06; A61P25/28; A61P27/02; A61P29/00; A61P29/02; A61P35/00; A61P43/00; C07D513/04
Attorney, Agent or Firm:
Takao Hamano
Morita Tetsuji
Teruichi Hirai
Morita Tetsuji
Teruichi Hirai