Title:
同時光学診断および治療適用のための染料バイオコンジュゲート
Document Type and Number:
Japanese Patent JP2006503798
Kind Code:
A
Abstract:
Novel tumor specific phototherapeutic and photodiagnostic agents are disclosed. The compounds consist of a carbocyanine dye for visualization, photosensitizer for photodynamic treatment, and tumor receptor-avid peptide for site-specific delivery of the probe and phototoxic agent to diseased tissues. A combination of these elements takes full advantage of the unique and efficient properties of each component for an effective patient care management.
Inventors:
Samuel I Achirev
Ragaban Rajago Paran
Richard B. Doshaw
Joseph E. Bugaju
Ragaban Rajago Paran
Richard B. Doshaw
Joseph E. Bugaju
Application Number:
JP2003565320A
Publication Date:
February 02, 2006
Filing Date:
January 31, 2003
Export Citation:
Assignee:
Mallinckrodt INC.
International Classes:
C07K7/06; A61B1/00; A61K38/00; A61K41/00; A61K49/00; A61P35/00; C12Q1/04; G01N21/00; G01N21/17; G01N21/64; G01N29/00; A61B8/08
Attorney, Agent or Firm:
Aoyama Aoi
Mitsutaka Iwasaki
Shoji Nakajima
Kazuaki Kojima
Mitsutaka Iwasaki
Shoji Nakajima
Kazuaki Kojima