Title:
用量ダンピングの恐れを低減させた新規な薬物送達システムとしての徐放性固形製剤
Document Type and Number:
Japanese Patent JP2006507216
Kind Code:
A
Abstract:
A sustained/controlled release formulation with reduced risk of dose dumping and side effects combines two components: component (a) comprises a pharmaceutically active agent and a water-insoluble, but water-permeable polymer, whereas component (b) comprises a pharmaceutically active agent and a hydrophobic material. By changing the ratio of a pharmaceutically active agent and water-insoluble, but water-permeable polymer comprised in the component (a) and/or the ratio of the pharmaceutically active agent and hydrophobic material comprised in the component (b), and ideal release rate, with reduced risk of dose dumping and side effects, can easily be achieved.
Inventors:
Khan, The Hiruru, M., I.
Claya Chic, Alexandra
Knessewick, Tudravica
Voudpiya-Mundeik, Sniezana
Claya Chic, Alexandra
Knessewick, Tudravica
Voudpiya-Mundeik, Sniezana
Application Number:
JP2003572553A
Publication Date:
March 02, 2006
Filing Date:
March 27, 2002
Export Citation:
Assignee:
Pre-Birth Twist An Ye Lat Oy O
International Classes:
A61K9/22; A61K9/02; A61K9/16; A61K9/20; A61K9/36; A61K9/48; A61K31/196; A61K31/341; A61K31/4409; A61K31/64; A61K47/04; A61K47/12; A61K47/14; A61K47/26; A61K47/32; A61K47/38; A61K47/44; A61K47/46; A61K9/28
Attorney, Agent or Firm:
Takao Hamano
Morita Tetsuji
Teruichi Hirai
Morita Tetsuji
Teruichi Hirai
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