低酸素誘導性因子に関連した病状を治療するためのメルファレンのN-オキシドと誘導体

Japanese Patent JP2006508124

A

This invention relates to compounds which are N-oxides and derivatives thereof, as well as their use to treat HIF related diseases. These compounds have the general formula set out below and are used to treat a variety of diseases associated with HIF: wherein R is an alkyl, aryl, arakyl or derivatives thereof such as CH₃OCH₂CH₂-, CH₃CH₂OCH₂CH₂-, C₆H₅OCH₂CH₂-, C₆H₅CH₂-, CH₃(CH₂)₃OCH₂CH₂Cl; or any one of the following:

JP2008133271	COMPOSITION FOR PREVENTING AND/OR TREATING LIFESTYLE-RELATED DISEASES
WO/2020/254690	COMPOSITION MODULATING BOTULINUM NEUROTOXIN EFFECT
WO2004009072	TETRAPROPYLAMMONIUM TETRATHIOMOLYBDATE AND RELATED COMPOUNDS FOR ANTI-ANGIOGENIC THERAPIES

Kirk Patrick, Lynn
Powys, Garth
Welsh, Sarah, Jay.

JP2004551738A

March 09, 2006

November 03, 2003

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ProLooks Pharmaceuticals Corporation
Arizona Board of Regents, Acting on Behalf of the University of Arizona

A61K31/205; A61K31/195; A61K31/66; A61K31/664; A61P9/00; A61P35/00; A61P43/00; C07F9/6584

US5602278A

1997-02-11

Taro Yaguchi
Junichi Omori
Yasuaki Yamaguchi

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