Title:
フェキソフェナジン組成物および調製方法
Document Type and Number:
Japanese Patent JP2007500682
Kind Code:
A
Abstract:
A pharmaceutical composition comprising fexofenadine or a pharmaceutical acceptable salt thereof, about 10 wt. % to about 70 wt. % of lactose, and about 1 wt. % to about 40 wt. % of a low-substituted hydroxypropyl cellulose, wherein the weight percents are based on the total weight of the pharmaceutical composition. The fexofenadine compositions of the invention exhibit improved bioavailability as expressed as Cmax, the maximum amount of active ingredient found in the plasma, or as AUC, the area under the plasma concentration time curve.
Inventors:
Nanday, Indolanil
Patel, Ashitsuyu Anilbuhai
Sadatrezaei, Mohsen
Davila, Pablo
Canapure, birendra maheshatsupa
Durughkar, Slendra Wasdeorao
Patel, Ashitsuyu Anilbuhai
Sadatrezaei, Mohsen
Davila, Pablo
Canapure, birendra maheshatsupa
Durughkar, Slendra Wasdeorao
Application Number:
JP2006521550A
Publication Date:
January 18, 2007
Filing Date:
July 30, 2004
Export Citation:
Assignee:
SANDOZ AKTIENGESELLSCHAFT
International Classes:
A61K31/445; A61K9/20; A61K9/26; A61K9/28; A61K47/26; A61K47/38; A61P11/08; A61P37/08; A61P43/00
Attorney, Agent or Firm:
Yoshio Kawaguchi
Makoto Ono
Chihiro Watanabe
Kenkyo Kanayama
Katsuma Osaki
Mitsuaki Tsubokura
Makoto Ono
Chihiro Watanabe
Kenkyo Kanayama
Katsuma Osaki
Mitsuaki Tsubokura