心臓血管疾患治療用のアンギオテンシン-II受容体遮断薬としてのロサルタン、バルサルタン、カンデサルタン、テルミサルタン、エプロサルタンおよびオルメサルタンのニトロオキシ誘導体

Title:

Document Type and Number:

Japanese Patent JP2007500684

Kind Code:

A

Abstract:

Angiotensin II receptor blocker nitroderivatives of formula (I): R-(Y-ONO₂)_s (I) having wider pharmacological activity and enhanced tolerability. They can be employed for treating cardiovascular, renal and chronic liver diseases and inflammatory processes.

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Inventors:

Almirante, Nicoletta
Del Soldato, Clown
Onzini, Ennio

Application Number:

JP2006521571A

Publication Date:

January 18, 2007

Filing Date:

July 20, 2004

Export Citation:

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Assignee:

NICOX S.A.

International Classes:

C07D235/20; A61K31/41; A61K31/4178; A61K31/4184; A61K45/00; A61P1/16; A61P7/02; A61P9/00; A61P9/04; A61P9/10; A61P9/12; A61P13/12; A61P29/00; C07D257/04; C07D403/10; C07D409/06

Domestic Patent References:

JP2002541233A	2002-12-03
JP2002541233A	2002-12-03

Foreign References:

WO2003013499A2	2003-02-20
WO2003013499A2	2003-02-20

Attorney, Agent or Firm:

Shintaro Nogawa

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