Title:
有効成分の制御送達のためのOROSプッシュ-スティック
Document Type and Number:
Japanese Patent JP2007506774
Kind Code:
A
Abstract:
A sustained release dosage form is provided comprising a pharmaceutically active agent and pharmaceutically acceptable salts thereof and adapted to release as an erodible solid over a prolonged period of time, wherein the dosage form provides burst release of the pharmaceutically active agent without the use of an immediate release drug coating. The dosage form is able to deliver high doses of poorly soluble or slowly dissolving active agents at a controlled rate. Methods of using the dosage forms to treat disease or conditions in human patients are also disclosed.
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Inventors:
Cruz, evangeline
Application Number:
JP2006528249A
Publication Date:
March 22, 2007
Filing Date:
September 24, 2004
Export Citation:
Assignee:
Alza Corporation
International Classes:
A61K9/20; A61K9/00; A61K9/22; A61K9/24; A61K9/36; A61K9/48; A61K31/00; A61K31/165; A61K31/192; A61K31/485; A61K45/00; A61K47/12; A61K47/20; A61K47/26; A61K47/32; A61K47/34; A61K47/38; A61K9/50
Domestic Patent References:
| JPH05194227A | 1993-08-03 | |||
| JP2000516637A | 2000-12-12 | |||
| JP2002531499A | 2002-09-24 | |||
| JP2001527034A | 2001-12-25 | |||
| JP2002528486A | 2002-09-03 |
Foreign References:
| US4915954A | 1990-04-10 |
Attorney, Agent or Firm:
Heikichi Odashima