Title:
骨形成タンパクのCD4+エピトープ
Document Type and Number:
Japanese Patent JP2007514411
Kind Code:
A
Abstract:
The present invention provides CD4+ T-cell epitopes in bone morphogenetic proteins (BMPs). In particular embodiments, the present invention provides CD4+ T-cell epitopes of BMP-7 and BMP-14. In some preferred embodiments, the present invention provides CD4+ T-cell epitopes of BMP-7 and BMP-14 that are suitable for modification to reduce the immunogenicity of the BMP-7 and BMP-14 proteins.
Inventors:
Harding, Fiona A.
Application Number:
JP2006539527A
Publication Date:
June 07, 2007
Filing Date:
October 21, 2004
Export Citation:
Assignee:
Genenco International Inc.
International Classes:
C12Q1/02; C07K14/51; C12P21/00; G01N33/53; G01N33/567; G01N33/74; A61K38/00; A61P13/12; A61P19/00; A61P19/10; C07K
Foreign References:
| WO2003042656A2 | 2003-05-22 | |||
| WO2002077187A2 | 2002-10-03 |
Attorney, Agent or Firm:
Yuzo Yamazaki
Naoto Sugiyama
Shirogane Expo
Toshiaki Akamatsu
Okuko Masako
Ichiro Tasaka
Takako Hoshi
Ono Wataru
Naoto Sugiyama
Shirogane Expo
Toshiaki Akamatsu
Okuko Masako
Ichiro Tasaka
Takako Hoshi
Ono Wataru