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Title:
疼痛の処置のための1-[2H-1-ベンゾピラン-2-オン-8-イル]-ピペラジン誘導体
Document Type and Number:
Japanese Patent JP2007530509
Kind Code:
A
Abstract:
The invention relates to a novel use of known 1-[2H-1-benzopyran-2-one-8-yl]-piperazine derivatives, broad spectrum 5-HT receptor binding compounds, having amongst other functional serotonin receptor activities, potent 5-HT1A-agonistic as well as 5-HT1D-antagonistic activity. The compounds of the invention are useful for the preparation of medicaments for treating pain. The invention relates to compounds of the general formula (1) wherein the symbols have the meanings as given in the description

Inventors:
Backzker, Cornelis
Glenon, The Free
Hethelink, Mike Bee
Taete, Claudia
Makuriri, Andrew
Van Schialenburg, Gustav J.A.M.
Application Number:
JP2007504418A
Publication Date:
November 01, 2007
Filing Date:
March 23, 2005
Export Citation:
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Assignee:
Solvay Pharmaceuticals B.V.
International Classes:
A61K45/00; A61K31/496; A61P25/04; A61P43/00; C07D405/04
Domestic Patent References:
JP2001520225A2001-10-30
JP2002511469A2002-04-16
JP2002533463A2002-10-08
JP2007530507A2007-11-01
Foreign References:
EP0650964A11995-05-03
Attorney, Agent or Firm:
Heikichi Odashima