ビタミンB1の前駆体の製造方法

Japanese Patent JP2008528529

A

The present invention relates to a novel process for the manufacture of Grewe-diamine comprising the following step: hydrolyzing a compound of formula (II), wherein R is hydrogen or straight- or branched chain C1-4 alkyl, with an aqueous alkali or alkaline-earth metal hydroxide solution, characterized in that the hydrolysis is carried out in the presence of an organic solvent.

WO/1995/002591	TRI-SUBSTITUTED IMIDAZOLES HAVING MULTIPLE THERAPEUTIC PROPERTIES
JPWO2006083010	Method for producing 4-acetylpyrimidine compound and its crystal

Bonras, Warner
Fishesser, Jocelyn
Giraudy, Lisa
Karge, Reinhard

JP2007552562A

July 31, 2008

January 24, 2006

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DSM IP ASSETS B.V.

C07D239/42; C07D415/00; C07B61/00

JP2001316377A	2001-11-13
JPS5576084A	1980-06-07

JPN7012000481; ルーマニア特許出願公開第７６８９１号明細書
JPN6012006802; 日本化学会編　第４版実験化学講座２０　有機合成ＩＩ　アルコール・アミン , 19920706, 第２９２頁, 丸善株式会社

Yuichi Yamada
Masakazu Noda
Yoshinori Shimizu

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