Title:
滅菌医薬粉末化合物の調製方法
Document Type and Number:
Japanese Patent JP2009514833
Kind Code:
A
Abstract:
The invention relates to a process for the preparation of pharmaceutical powders, the process comprising: a) solubilization of the pharmaceutical compound in water or in an organic solvent at a concentration close to saturation; b) evaporating the solvent at constant temperature while subjecting the solution to ultrasound. In another embodiment, the invention relates to a process for the preparation of sterile pharmaceutical compounds, the process comprising: a) solubilization of the pharmaceutical compound in water or in an organic solvent at a concentration close to saturation; b) sterilizing filtration of the solution by passing it through a hydrophobic filter (0,22 microns membrane); c) evaporating the solvent at constant temperature while subjecting the solution to ultrasound.
Inventors:
Vincenzo de Tomasso
Application Number:
JP2008538349A
Publication Date:
April 09, 2009
Filing Date:
October 30, 2006
Export Citation:
Assignee:
Pharmatex Italia Esselle Elle
International Classes:
A61K31/58; A61K9/14; A61P29/00
Attorney, Agent or Firm:
Masatake Shiga
Takashi Watanabe
Yasuhiko Murayama
Shinya Mitsuhiro
Takashi Watanabe
Yasuhiko Murayama
Shinya Mitsuhiro