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Title:
(R)-トフィソパムを単離する方法
Document Type and Number:
Japanese Patent JP2009519938
Kind Code:
A
Abstract:
The present invention is directed to a process for the isolation of (R)-tofisopam with high enantiomeric purity and high overall yields from a mixture of tofisopam enantiomers by means of a non-steady state continuous chromatographic process.

Inventors:
Scott Earl Perrin
Naydon Ye
Kim B. Galbraith
Wilhelm Hauck
Application Number:
JP2008545795A
Publication Date:
May 21, 2009
Filing Date:
December 13, 2006
Export Citation:
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Assignee:
Vera Acquisition Corporation
International Classes:
C07D243/02; A61K31/5513; A61P25/22; C07B57/00; C07D243/10; A61K31/551
Domestic Patent References:
JP2002528738A2002-09-03
JP2005507935A2005-03-24
Foreign References:
US20040162284A12004-08-19
US20040254174A12004-12-16
Attorney, Agent or Firm:
Axis International Patent Business Corporation