Title:
(R)-トフィソパムを単離する方法
Document Type and Number:
Japanese Patent JP2009519938
Kind Code:
A
Abstract:
The present invention is directed to a process for the isolation of (R)-tofisopam with high enantiomeric purity and high overall yields from a mixture of tofisopam enantiomers by means of a non-steady state continuous chromatographic process.
Inventors:
Scott Earl Perrin
Naydon Ye
Kim B. Galbraith
Wilhelm Hauck
Naydon Ye
Kim B. Galbraith
Wilhelm Hauck
Application Number:
JP2008545795A
Publication Date:
May 21, 2009
Filing Date:
December 13, 2006
Export Citation:
Assignee:
Vera Acquisition Corporation
International Classes:
C07D243/02; A61K31/5513; A61P25/22; C07B57/00; C07D243/10; A61K31/551
Domestic Patent References:
JP2002528738A | 2002-09-03 | |||
JP2005507935A | 2005-03-24 |
Foreign References:
US20040162284A1 | 2004-08-19 | |||
US20040254174A1 | 2004-12-16 |
Attorney, Agent or Firm:
Axis International Patent Business Corporation