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Title:
皮膚科学的状態を処置するための組成物および方法
Document Type and Number:
Japanese Patent JP2009519940
Kind Code:
A
Abstract:
The present invention is drawn to solidifying adhesive formulations, methods of drug delivery, and solidified layers for dermal delivery of a drug which can treat various dermatological conditions, such as a bacterial infection, a virus infection, a fungal infection, alopecia, dermatitis, psoriasis, or photo damaged skin. The formulation can include a drug, a solvent vehicle, and a solidifying agent. The solvent vehicle can include a volatile solvent system including at least one volatile solvent, and a non-volatile solvent system including at least one non-volatile solvent. The non-volatile solvent system can facilitate the delivery of the drug at therapeutically effective rates for sustained period of time. The non-volatile solvent system can also act as a plasticizer for the solidifying agent. The formulation can have a viscosity suitable for application to a skin surface prior to evaporation of the volatile solvents system. When applied to the skin, the formulation can form a solidified layer after at least a portion of the volatile solvent system is evaporated.

Inventors:
Chan, Chie
Warner, Kevin S.
Sharma, Sanjay
Application Number:
JP2008545816A
Publication Date:
May 21, 2009
Filing Date:
December 14, 2006
Export Citation:
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Assignee:
Tears, Inc.
International Classes:
A61K9/70; A61K47/06; A61K47/10; A61K47/12; A61K47/30; A61K47/38; A61P17/00; A61P31/12
Domestic Patent References:
JP2003510259A2003-03-18
JP2004520337A2004-07-08
JPH01110623A1989-04-27
JPH01110620A1989-04-27
JP2005503318A2005-02-03
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita