Title:
生体分子のクロマトグラフィー精製プロセスの最適化方法
Document Type and Number:
Japanese Patent JP2009539931
Kind Code:
A
Abstract:
The invention relates to a method of finding suitable parameters for the chromatographic purification of biomolecules. The method consists of equilibration, charging, washing and eluting steps, this sequence of steps being carried out by the partial batch method. The parameters determined in small, preferably numerous parallel test batches provide conclusions as to the chromatography conditions under which a given biomolecule can be purified optimally by column chromatography, optionally even on a larger scale.
Inventors:
Ecker man christian
Eberto Gibile
Ruben Wolf Stephanie
Ambrosius Dorothay
Eberto Gibile
Ruben Wolf Stephanie
Ambrosius Dorothay
Application Number:
JP2009514784A
Publication Date:
November 19, 2009
Filing Date:
June 12, 2007
Export Citation:
Assignee:
Boehringer Ingelheim Pharma Gesellshaft Mitt Beschlenktel Haftung Und Company Comandito Gesellshaft
International Classes:
C07K1/16; B01D15/08; G01N30/86; G01N30/88
Foreign References:
| US20060096924A1 | 2006-05-11 | |||
| US20050176937A1 | 2005-08-11 |
Attorney, Agent or Firm:
Sadao Kumakura
Nobuo Ogawa
Atsushi Hakoda
Kenji Asai
Koji Hirayama
Akizawa
Nobuo Ogawa
Atsushi Hakoda
Kenji Asai
Koji Hirayama
Akizawa