Title:
脂質レベルの上昇に関連する疾病の処置に適するヘテロ環式化合物
Document Type and Number:
Japanese Patent JP2010501488
Kind Code:
A
Abstract:
The present invention provides heterocyclic derivatives that modulate the activity of stearoyl-CoA desaturase. Methods of using such derivatives to modulate the activity of stearoyl-CoA desaturase and pharmaceutical compositions comprising such derivatives are also encompassed.
Inventors:
Natalie Dales
Julia Fonarev
Jiang Min Hu
Legend Kambogy
Vishnu Mercy Kodomur
Schiffen Liu
Natalia Pokrovskya
Vandona Raina
Xiao Soon
Zaifui Chan
Julia Fonarev
Jiang Min Hu
Legend Kambogy
Vishnu Mercy Kodomur
Schiffen Liu
Natalia Pokrovskya
Vandona Raina
Xiao Soon
Zaifui Chan
Application Number:
JP2009524754A
Publication Date:
January 21, 2010
Filing Date:
August 13, 2007
Export Citation:
Assignee:
NOVARTIS AG
International Classes:
C07D409/04; A61K31/4178; A61K31/4196; A61K31/422; A61K31/423; A61K31/4245; A61K31/427; A61K31/428; A61K31/433; A61K31/4439; A61K31/444; A61K31/454; A61K31/4709; A61K31/4725; A61K31/497; A61K31/501; A61K31/506; A61K31/513; A61K31/695; A61P1/14; A61P1/16; A61P1/18; A61P3/00; A61P3/04; A61P3/06; A61P3/10; A61P5/24; A61P7/00; A61P7/02; A61P9/00; A61P9/10; A61P9/12; A61P11/06; A61P15/00; A61P17/00; A61P17/02; A61P17/04; A61P19/02; A61P19/06; A61P21/00; A61P25/00; A61P25/18; A61P27/02; A61P27/16; A61P29/00; A61P31/14; A61P31/16; A61P31/18; A61P35/00; A61P35/04; A61P37/02; A61P43/00; C07D409/14; C07D413/14; C07D417/04; C07D417/14; C07F7/18
Domestic Patent References:
| JPH11193281A | 1999-07-21 | |||
| JP2002302488A | 2002-10-18 | |||
| JPH1192370A | 1999-04-06 | |||
| JPS63239281A | 1988-10-05 | |||
| JPS4970968A | 1974-07-09 | |||
| JP2002515014A | 2002-05-21 | |||
| JPS52148072A | 1977-12-08 | |||
| JP2004536798A | 2004-12-09 |
Foreign References:
| WO2006034440A2 | 2006-03-30 | |||
| WO2004009558A2 | 2004-01-29 | |||
| US5451592A | 1995-09-19 | |||
| US20030087936A1 | 2003-05-08 | |||
| GB986562A | 1965-03-17 | |||
| CH455806A | 1968-05-15 | |||
| NL6511486A | 1966-03-04 | |||
| US4086240A | 1978-04-25 | |||
| CH463517A | 1968-10-15 | |||
| WO2004096781A1 | 2004-11-11 |
Attorney, Agent or Firm:
Mitsuo Tanaka
Takuji Yamada
Mitsutaka Iwasaki
Aoyama Aoi
Masayuki Nakagawa
Takuji Yamada
Mitsutaka Iwasaki
Aoyama Aoi
Masayuki Nakagawa