Title:
POSH及びPOSH-AP阻害剤としてのピリミジン誘導体
Document Type and Number:
Japanese Patent JP2010509205
Kind Code:
A
Abstract:
Pyrimidine deriviatives are ubiquination inhibitors that inhibit the ubiquitin ligase activity, particularly of POSH polypeptides, are useful for the treatment of viral infections and neurological disorders.
Inventors:
Nakahe, Philip
Angel, Ichek
Ribner, Nurit
Borobitov, Maxim
Angel, Ichek
Ribner, Nurit
Borobitov, Maxim
Application Number:
JP2009535189A
Publication Date:
March 25, 2010
Filing Date:
November 07, 2007
Export Citation:
Assignee:
Proteology Limited
International Classes:
C07D409/14; A61K31/506; A61P9/00; A61P25/00; A61P25/14; A61P25/16; A61P25/18; A61P25/24; A61P25/28; A61P43/00; C07K5/06; C12N9/99
Foreign References:
WO2005013914A2 | 2005-02-17 | |||
US20060014807A1 | 2006-01-19 |
Other References:
JPN6013000721; Journal of Combinatorial Chemistry Vol.8, No.3, 2006, p.326-337
JPN6013000723; Sulfur Letters Vol.24, No.4, 2001, p.151-179
JPN6013000717; 'Synthesis of some new heterobicyclic compound bearing chromon-3-yl moiety and related compounda as a' Chemical abstracts Vol.127, 1997, 34170h,34171a
JPN6013000719; Registry No.326026-75-9,Registry [online]; Retrieved from STN , 20010307
JPN6013000723; Sulfur Letters Vol.24, No.4, 2001, p.151-179
JPN6013000717; 'Synthesis of some new heterobicyclic compound bearing chromon-3-yl moiety and related compounda as a' Chemical abstracts Vol.127, 1997, 34170h,34171a
JPN6013000719; Registry No.326026-75-9,Registry [online]; Retrieved from STN , 20010307
Attorney, Agent or Firm:
Asamura patent office
Hideto Asamura
Hajime Asamura
Mari Yuge
Naganuma Akio
Yukihiro Ikeda
Kajiwara Saiko
Shinmura Morio
Kanamori Koji
Yuko Nagase
Youichi Inoue
Hideto Asamura
Hajime Asamura
Mari Yuge
Naganuma Akio
Yukihiro Ikeda
Kajiwara Saiko
Shinmura Morio
Kanamori Koji
Yuko Nagase
Youichi Inoue