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Title:
鎮痛化合物
Document Type and Number:
Japanese Patent JP2010534192
Kind Code:
A
Abstract:
The invention refers to novel compounds (e.g., peptides) that are useful in the treatment of pain. The compounds are useful in treating both chronic and acute pain. The peptides can act as analgesics and/or anti-nociceptive agents. According to an embodiment, the invention refers to an isolated peptide that comprises an amino acid sequence that is at least 70% identical to the 14 amino acid sequence: pGlu-Phe-Ser-Pro-Glu-Asn-Ala-Gln-Gly-Glu-Ser-Gln-Pro-Ala (SEQ ID NO:2).

Inventors:
Cree, Yarra
Piccolo, Giselle
Konno, Katsuhiro
Application Number:
JP2010504392A
Publication Date:
November 04, 2010
Filing Date:
April 30, 2008
Export Citation:
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Assignee:
Fundacao de Amparo a Pesquiza do Estado de Sao Paulo-Ehui a p e e ci pé
Biosynthetica Huarmaseuchika Limitada
Cree, Yarra
International Classes:
C07K7/08; A61K38/22; A61P17/04; A61P25/04; A61P43/00
Domestic Patent References:
JP2005506300A2005-03-03
JP2003531636A2003-10-28
Foreign References:
US5232911A1993-08-03
WO2005107357A22005-11-17
WO2007018047A12007-02-15
Other References:
JPN6012060984; Biochimica et biophysica acta. 1990, Vol.1037, No.3, p.413-421
Attorney, Agent or Firm:
Yoshio Kawaguchi
Chihiro Watanabe
Katsuma Osaki
Mitsuaki Tsubokura