Title:
神経系障害の新規な処置法
Document Type and Number:
Japanese Patent JP2010534194
Kind Code:
A
Abstract:
Provided are novel drugs and methods in the treatment as well as diagnosis of neurological disorders such as Alzheimer's disease and amyloid-beta pathology/amyloidosis. More specifically, the use of erythropoietin and analogs thereof for the treatment of Aβ peptide related brain impairments is described. Furthermore, the use of claudin-5 and variants thereof as biomarker for Alzheimer's disease and for the progression of Alzheimer's disease, respectively, is provided.
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Inventors:
Grimm, Yang
Niche, roger
Chen, Feng
Niche, roger
Chen, Feng
Application Number:
JP2010511545A
Publication Date:
November 04, 2010
Filing Date:
June 16, 2008
Export Citation:
Assignee:
UNIVERSITAT ZURICH
International Classes:
A61K38/22; A61K39/395; A61K45/00; A61P25/00; A61P25/28; G01N33/68
Domestic Patent References:
| JPH0592928A | 1993-04-16 | |||
| JPH05246885A | 1993-09-24 | |||
| JP2005514394A | 2005-05-19 | |||
| JPH08506023A | 1996-07-02 |
Foreign References:
| WO2007060213A2 | 2007-05-31 | |||
| WO2006109698A1 | 2006-10-19 | |||
| US20060246075A1 | 2006-11-02 | |||
| WO2005028511A2 | 2005-03-31 |
Other References:
JPN6012060141; Ｍｅｔａｂｏｌｉｃ Ｂｒａｉｎ Ｄｉｓｅａｓｅ Ｖｏｌ．１９， Ｎｏ．３／４, 2004, ｐ．１９５-２０６
Attorney, Agent or Firm:
Mikiharu Hagino