Title:
2-アルコキシメチレン-4,4-ジフルオロ-3-オキソ酪酸アルキルの製造方法
Document Type and Number:
Japanese Patent JP2011513282
Kind Code:
A
Abstract:
A process for preparing alkyl 2-alkoxymethylene-4,4-difluoro-3-oxobutyrates (VI) where R is methyl or ethyl, from crude reaction mixtures of alkyl 4,4-difluoroacetoacetates (I) by a) reacting where M is a sodium or potassium ion, and without additional solvent to form an enolate (V) b) releasing the corresponding alkyl 4,4-difluoroacetoacetate (I) from the enolate (V) by means of acid, c) removing the salt formed from cation M and acid anion as a solid and d) converting (I), without isolation from the crude reaction mixture, to the alkyl 2-alkoxymethylene-4,4-difluoro-3-oxobutyrate (VI), and the use of (VI) for preparing 1-methyl-3-difluoromethyl-pyrazol-3-ylcarboxyates VII
Inventors:
My wald, volker
Schmidt, Sebastian Pale
Wolf, Bernd
Choradin, christopher
Zielke, Thomas
Rack, michael
Kyle, Michael
Schmidt, Sebastian Pale
Wolf, Bernd
Choradin, christopher
Zielke, Thomas
Rack, michael
Kyle, Michael
Application Number:
JP2010548124A
Publication Date:
April 28, 2011
Filing Date:
February 27, 2009
Export Citation:
Assignee:
BASF SE
International Classes:
C07C67/343; C07C69/738; C07D231/14
Domestic Patent References:
| JPH07501549A | 1995-02-16 |
Foreign References:
| WO2006090778A1 | 2006-08-31 | |||
| WO2007115766A1 | 2007-10-18 |
Attorney, Agent or Firm:
Yusuke Hiraki
Satoshi Fujita
Eiichi Arai
Natsuo Tanaka
Satoshi Fujita
Eiichi Arai
Natsuo Tanaka
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