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Title:
κオピオイド受容体リガンド
Document Type and Number:
Japanese Patent JP2011518159
Kind Code:
A
Abstract:
Kappa opioid receptor antagonists are provided that yield significant improvements in functional binding assays to kappa opioid receptors, and the use of these antagonists in treatment of disease states that are ameliorated by binding of the kappa opioid receptor such as heroin or cocaine addictions.

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Inventors:
Frank Ivy Carroll
Helnan A Navarro
James B. Thomas
Tin Way Kai
Application Number:
JP2011505043A
Publication Date:
June 23, 2011
Filing Date:
February 06, 2009
Export Citation:
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Assignee:
Research Triangle Institute
International Classes:
C07D401/12; A61K31/4725; A61P1/12; A61P3/04; A61P9/12; A61P11/06; A61P13/02; A61P19/02; A61P25/06; A61P25/08; A61P25/18; A61P25/20; A61P25/24; A61P25/30; A61P31/12; A61P35/00; A61P37/02; A61P37/06; A61P37/08; A61P43/00
Domestic Patent References:
JP2004521100A2004-07-15
JP2006520361A2006-09-07
Foreign References:
WO2006089130A12006-08-24
Attorney, Agent or Firm:
Yasuhiko Murayama
Masatake Shiga
Takashi Watanabe
Shinya Mitsuhiro



 
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