Title:
エラスチン様ペプチドを含む治療剤
Document Type and Number:
Japanese Patent JP2011526303
Kind Code:
A
Abstract:
The present invention provides therapeutic agents and compositions comprising elastin-like peptides(ELPs) and therapeutic protein is a GLP-1 receptor agonist, insulin, or Factor VII/VIIa, including functional analogs. The present invention further provides encoding polynucleotides, as well as methods of making and using the therapeutic agents. The therapeutic agents have improvements in relation to their use as therapeutics, including, inter alia, one or more of half-life, clearance and/or persistence in the body, solubility, and bioavailability.
Inventors:
Chirkoty, Ashtosh
Application Number:
JP2011516765A
Publication Date:
October 06, 2011
Filing Date:
June 29, 2009
Export Citation:
Assignee:
DUKE UNIVERSITY
International Classes:
A61K38/17; A61K38/00; A61K45/00; A61P3/10; A61P7/04; A61P43/00; C12N1/19; C12N1/21; C12N5/10; C12N15/09; C07K14/78; C12N1/15
Foreign References:
| WO2008030968A2 | 2008-03-13 | |||
| WO2007073486A2 | 2007-06-28 | |||
| WO2007024427A1 | 2007-03-01 |
Other References:
JPN6013063304; ＤＩＡＢＥＴＥＳ／ＭＥＴＡＢＯＬＩＳＭ ＲＥＳＥＡＲＣＨ ＡＮＤ ＲＥＶＩＥＷＳ Ｖｏｌ． ２１, 2005, ｐｐ．３１３-３３１
Attorney, Agent or Firm:
Yoshiyuki Inaba
Toshifumi Onuki
Toshifumi Onuki