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Title:
21位の芳香族リンカーを介して硝酸エステルに結合したグルココルチコイド類および眼科におけるそれらの使用
Document Type and Number:
Japanese Patent JP2011529461
Kind Code:
A
Abstract:
The invention relates to nitrooxy derivatives of fluocinolone acetonide, triamcinolone acetonide, betamethasone and beclomethasone, methods for their preparation, pharmaceutical compositions containing these compounds, and methods of using these compounds and compositions for treating diabetic macular edema, diabetic retinopathy, macular degeneration, age-related macular degeneration and other diseases of retina and macula lutea.

Inventors:
Benedini, Francesca
Bonfanti, Anna Lisa
Tyrol, Valerio
Stelle, Rebecca
Ongini, Ennio
Biondi, Stefano
Application Number:
JP2011520413A
Publication Date:
December 08, 2011
Filing Date:
July 07, 2009
Export Citation:
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Assignee:
NICOX S.A.
International Classes:
C07J71/00; A61K31/58; A61P9/10; A61P27/02; A61P29/00
Domestic Patent References:
JP2000509016A2000-07-18
JP2000509388A2000-07-25
JP2000509072A2000-07-18
JP2005516070A2005-06-02
JP2000509016A2000-07-18
JP2000509388A2000-07-25
JP2000509072A2000-07-18
Foreign References:
EP1336602A12003-08-20
WO2007025632A22007-03-08
EP1336602A12003-08-20
Attorney, Agent or Firm:
Shintaro Nogawa
Masanori Akiyama
Shinji Kai
Yusuke Kaneko
Kiyoshi Inamoto