G6PC2コードβ細胞表面タグ

Title:

G6PC2コードβ細胞表面タグ

Document Type and Number:

Japanese Patent JP2012504230

Kind Code:

A

Abstract:

The invention relates to G6PC2-encoded beta cell surface markers, methods of identifying and obtaining a culture cells comprising fully differentiated beta cells. Also contemplated is a method of sorting such cells, isolated cells and compositions thereof.

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Inventors:

Burt Loop
Jacob Hult
Ole Drags Burke Madsen

Application Number:

JP2011528369A

Publication Date:

February 16, 2012

Filing Date:

September 30, 2009

Export Citation:

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Assignee:

Novo Nordisk Ar/S

International Classes:

G01N33/53; A61L27/00; C07K16/28; C12N5/07; C12Q1/04; A61K35/12

Domestic Patent References:

JP2009501002A	2009-01-15
JP2006525813A	2006-11-16
JP2006506084A	2006-02-23

Foreign References:

WO2005030032A2	2005-04-07
WO2007103282A2	2007-09-13

Other References:

JPN6013053910; Ｊ．　-Ｊ．　Ｓｈｉｅｈ，　Ｃ．　-Ｊ．　Ｐａｎ，　Ｂ．　Ｃ．　Ｍａｎｓｆｉｌｄ，　Ｊ．　Ｙ．　Ｃｈｏｕ: 'Ｉｎ　Ｉｓｌｅｔ-ｓｐｅｃｉｆｉｃ　ｇｌｕｃｏｓｅ-６-ｐｈｏｓｐｈａｔａｓｅ-ｒｅｌａｔｅｄ　ｐｒｏｔｅｉｎ，　ｔｈｅ　ｂｅｔａ　ｃｅｌｌ　ａｎｔｉｇｅｎｉｃ　ｓｅｑｕｅｎｃｅ　ｔｈａｔ　ｉｓ　ｔａ' ＤｉａｂｅｔｏｌｏｇｉａＶｏｌ．　４８：　１８５１-１８５９, 2005
JPN5012000425; ＫＯＢＬＡＳ　Ｔ: 'ＤＩＦＦＥＲＥＮＴＩＡＴＩＯＮ　ＯＦ　ＣＤ１３３-ＰＯＳＩＴＩＶＥ　ＰＡＮＣＲＥＡＴＩＣ　ＣＥＬＬＳ　ＩＮＴＯ　ＩＮＳＵＬＩＮ-ＰＲＯＤＵＣＩＮＧ　ＩＳＬＥＴ-ＬＩＫＥ　ＣＥＬＬ　ＣＬＵＳＴＥＲＳ' ＴＲＡＮＳＰＬＡＮＴＡＴＩＯＮ　ＰＲＯＣＥＥＤＩＮＧＳＶ４０　Ｎ２, 20080301, Ｐ４１５-４１８
JPN6013053907; Ｃｙｒｕｓ　Ｃ．　Ｍａｒｔｉｎ．　Ｌａｒｒｙ　Ｊ．　Ｂｉｓｃｈｏｆ，　Ｂａｒｂａｒａ　Ｂｅｒｇｍａｎ，　ｅｔ　ａｌ．: 'Ｃｌｏｎｉｎｇ　ａｎｄ　Ｃｈａｒａｃｔｅｒｉｚａｔｉｏｎ　ｏｆ　ｔｈｅ　Ｈｕｍａｎ　ａｎｄ　Ｒａｔ　Ｉｓｌｅｔ-ｓｐｅｃｉｆｉｃ　Ｇｌｕｃｏｓｅ-６-ｐｈｏｓｐｈａｔａｓｅ　Ｃａｔａｌｙｔｉｃ　Ｓｕｂ' Ｊｏｕｒｎａｌ　ｏｆ　Ｂｉｏｌｏｇｉｃａｌ　ＣｈｅｍｉｓｔｒｙＶｏｌ．　２７６，　Ｎｏ．　２７．　ｐｐ．　２５１９７-２５２０７, 20010706

Attorney, Agent or Firm:

Yasuhiko Murayama
Masatake Shiga
Takashi Watanabe
Shinya Mitsuhiro

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