Title:
アポトーシスプロモーターの脂質製剤
Document Type and Number:
Japanese Patent JP2012525434
Kind Code:
A
Abstract:
An orally deliverable pharmaceutical composition comprises a drug-carrier system having a Bcl-2 family protein inhibitory compound, e.g., ABT-263, in solution in a substantially non-aqueous carrier that comprises at least one phospholipid and a pharmaceutically acceptable solubilizing agent. The composition is suitable for oral administration to a subject in need thereof for treatment of a disease characterized by overexpression of one or more anti-apoptotic Bcl-2 family proteins, for example cancer.
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Inventors:
David, Paul
Fitx, Michael
Fisher, Christina
Hate, Anthony Earl
Haemstra, kyasarin
Marseille, Kenan
Peter mayer
Rubin, Bittery
Santsugiri, Yes Yuonto
Schmitt, Eric
Ton, pin
Doyouan, Dorian
Fitx, Michael
Fisher, Christina
Hate, Anthony Earl
Haemstra, kyasarin
Marseille, Kenan
Peter mayer
Rubin, Bittery
Santsugiri, Yes Yuonto
Schmitt, Eric
Ton, pin
Doyouan, Dorian
Application Number:
JP2012508758A
Publication Date:
October 22, 2012
Filing Date:
April 30, 2010
Export Citation:
Assignee:
ABBOTT LABORATORIES
International Classes:
A61K31/635; A61K9/48; A61K47/10; A61K47/24; A61P35/00; A61P35/02; A61P43/00
Attorney, Agent or Firm:
Kawaguchi International Patent Office