Title:
除去されたエフェクター機能を伴う抗体Fc突然変異
Document Type and Number:
Japanese Patent JP2013512258
Kind Code:
A
Abstract:
Antibody and other Fc-containing molecules with variations in the Fc region reduce binding to Fc gamma receptors and resulting activity and can be used in the treatment of various diseases and disorders.
Inventors:
Stroll, William
Buffer, Omid
Buffer, Omid
Application Number:
JP2012541220A
Publication Date:
April 11, 2013
Filing Date:
November 29, 2010
Export Citation:
Assignee:
Janssen Biotech, Inc.
International Classes:
C07K16/28; A61K39/395; A61K39/44; A61P1/04; A61P7/04; A61P7/06; A61P9/00; A61P9/10; A61P11/06; A61P17/00; A61P19/02; A61P25/28; A61P29/00; A61P37/06; A61P37/08; A61P43/00; C07K19/00
Domestic Patent References:
| JP2003512019A | 2003-04-02 |
Foreign References:
| US5834597A | 1998-11-10 |
Other References:
JPN6015003003; Ｃｕｒｒ．Ｏｐｉｎ．Ｂｉｏｔｅｃｈｎｏｌ．，２００９，２０（６），ｐ．６８５-９１
Attorney, Agent or Firm:
Hiroshi Kobayashi
Junko Kobayashi
Norio Omori
Yasuhito Suzuki
Junko Kobayashi
Norio Omori
Yasuhito Suzuki