Title:
コンジュゲートFVIIIバリアント
Document Type and Number:
Japanese Patent JP2013519636
Kind Code:
A
Abstract:
The present invention relates to a recombinant Factor VIII molecule, wherein said molecule has reduced vWF binding capacity, and wherein said molecule is covalently conjugated with at least one side group.
Inventors:
Karsten Behrens
Jens Buchart
Magali Tundel
Jens Buchart
Magali Tundel
Application Number:
JP2012552352A
Publication Date:
May 30, 2013
Filing Date:
February 07, 2011
Export Citation:
Assignee:
Novo Nordisk Ar/S
International Classes:
A61K38/43; C07K14/755; A61K47/34; A61K47/36; A61K47/48; A61P7/04; C12N15/09
Foreign References:
| WO2009108806A1 | 2009-09-03 | |||
| WO2009062100A1 | 2009-05-14 | |||
| WO2010014708A2 | 2010-02-04 |
Other References:
JPN6015016800; Ｈａｅｍｏｐｈｉｌｉａ ｖｏｌ．１２， ｓｕｐｐｌ．３, 2006, ｐｐ．４２-５１
Attorney, Agent or Firm:
Yasuhiko Murayama
Masatake Shiga
Takashi Watanabe
Shinya Mitsuhiro
Masatake Shiga
Takashi Watanabe
Shinya Mitsuhiro