Title:
血清アミロイドP成分に特異的な抗原結合タンパク質
Document Type and Number:
Japanese Patent JP2013521252
Kind Code:
A
Abstract:
The present invention relates to antigen binding proteins, such as antibodies, which bind to serum amyloid P component (SAP), polynucleotides encoding such antigen binding proteins, pharmaceutical compositions comprising said antigen binding proteins and methods of manufacture. The present invention also concerns the use of such antigen binding proteins in the treatment or prophylaxis of diseases associated with amyloid deposition including systemic amyloidosis, local amyloidosis, Alzheimer's disease, and type 2 diabetes.
Inventors:
Binder, Tesinder, Cowl
Ford, Susanna, Karen
Germanium Shewski, Volker
Lewis, Alan, Peter
Peeps, mark, brian
Ford, Susanna, Karen
Germanium Shewski, Volker
Lewis, Alan, Peter
Peeps, mark, brian
Application Number:
JP2012555403A
Publication Date:
June 10, 2013
Filing Date:
March 01, 2011
Export Citation:
Assignee:
GLAXO GROUP LIMITED
International Classes:
C07K16/18; A61K39/395; A61P25/28; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/09; C12P21/08
Foreign References:
| WO2009155962A1 | 2009-12-30 | |||
| WO2009000926A1 | 2008-12-31 | |||
| WO1995005394A1 | 1995-02-23 |
Other References:
JPN6015012813; Ｍｅｔｈｏｄｓ ｉｎ Ｅｎｚｙｍｏｌｏｇｙ Ｖｏｌ．４１２, 2006, ｐ．１６１-１８２
JPN6015012813; Ｍｅｔｈｏｄｓ ｉｎ Ｅｎｚｙｍｏｌｏｇｙ Ｖｏｌ．４１２, 2006, ｐ．１６１-１８２
JPN6015012813; Ｍｅｔｈｏｄｓ ｉｎ Ｅｎｚｙｍｏｌｏｇｙ Ｖｏｌ．４１２, 2006, ｐ．１６１-１８２
Attorney, Agent or Firm:
Yusuke Hiraki
Satoshi Fujita
Eiichi Arai
Natsuo Tanaka
Satoshi Fujita
Eiichi Arai
Natsuo Tanaka