Title:
ヘキサヒドロピロロ[3,4-b]ピロール誘導体、その製造方法及び用途
Document Type and Number:
Japanese Patent JP2013526588
Kind Code:
A
Abstract:
Hexahydropyrrolo[3,4- b ] pyrrole derivatives, preparation methods and pharmaceutical uses thereof are provided. Specifically, dipeptidyl peptidase IV inhibitors presented by following formula (I) are provided. In the formula, each group is defined as in the description. Such compounds can be used for treating or preventing the diseases associated with dipeptidyl peptidase IV, such as diabetes, obesity and hyperlipemia. The compounds presented by formula (I) and pharmaceutically acceptable salts thereof, a method for preparing a pharmaceutical composition thereof and their uses in the manufacture of medicaments for treating or preventing the disease associated with dipeptidyl peptidase IV are provided.
Inventors:
Roh Peng
Zhang Sharp
At Manmatsu
Zhu Ming Jie
Chen Righteousness
Zhang Sharp
At Manmatsu
Zhu Ming Jie
Chen Righteousness
Application Number:
JP2013511511A
Publication Date:
June 24, 2013
Filing Date:
January 28, 2011
Export Citation:
Assignee:
Shanghai Yang Sailing Medicine Science and Technology Co., Ltd.
International Classes:
C07D487/04; A61K31/407; A61P3/04; A61P3/06; A61P3/10; A61P43/00
Foreign References:
| WO2006015699A1 | 2006-02-16 | |||
| WO2006099940A1 | 2006-09-28 | |||
| WO2006015699A1 | 2006-02-16 | |||
| WO2006099940A1 | 2006-09-28 | |||
| WO2008135141A1 | 2008-11-13 | |||
| WO2008109336A1 | 2008-09-12 | |||
| WO2008100565A1 | 2008-08-21 |
Attorney, Agent or Firm:
Yasuhiko Murayama
Masatake Shiga
Takashi Watanabe
Shinya Mitsuhiro
Masatake Shiga
Takashi Watanabe
Shinya Mitsuhiro