Title:
抗メソテリン抗体及びイムノコンジュゲート
Document Type and Number:
Japanese Patent JP2014509835
Kind Code:
A
Abstract:
The invention provides anti-mesothelin antibodies and immunoconjugates and methods of using the same.
Inventors:
Denise mark
Scales, Susanna J.
Spencer, Susan Dee.
Chang, Inn
Scales, Susanna J.
Spencer, Susan Dee.
Chang, Inn
Application Number:
JP2013544871A
Publication Date:
April 24, 2014
Filing Date:
December 19, 2011
Export Citation:
Assignee:
Genentech, Incorporated
International Classes:
C12N15/09; A61K31/7068; A61K38/00; A61K38/08; A61K39/395; A61K45/00; A61K51/00; A61P35/00; A61P43/00; C07K16/30; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12P21/08; G01N33/48; G01N33/53; G01N33/574
Domestic Patent References:
| JP2010513481A | 2010-04-30 | |||
| JP2008532523A | 2008-08-21 |
Foreign References:
| WO2009045957A1 | 2009-04-09 | |||
| WO2008072723A1 | 2008-06-19 | |||
| WO2010111282A1 | 2010-09-30 | |||
| WO2008141044A2 | 2008-11-20 | |||
| US20080248053A1 | 2008-10-09 | |||
| WO2010124797A1 | 2010-11-04 |
Other References:
HASSAN R. ET AL.: "Preclinical evaluation of MORAb-009, a chimeric antibody targeting tumor-associated mesothelin", CANCER IMMUN., vol. Vol.7, p.20, JPN6015043812, 19 December 2007 (2007-12-19), pages 1 - 10, ISSN: 0003188197
MOL. CANCER THER., vol. 8, no. 5, JPN6015043816, May 2009 (2009-05-01), pages 1113 - 1118, ISSN: 0003188198
CLIN CANCER RES., vol. 11, no. 16, JPN6015043818, 15 August 2005 (2005-08-15), pages 5840 - 5846, ISSN: 0003188199
MOL. CANCER THER., vol. 8, no. 5, JPN6015043816, May 2009 (2009-05-01), pages 1113 - 1118, ISSN: 0003188198
CLIN CANCER RES., vol. 11, no. 16, JPN6015043818, 15 August 2005 (2005-08-15), pages 5840 - 5846, ISSN: 0003188199
Attorney, Agent or Firm:
Sonoda Yoshitaka
Kobayashi Yoshinori
Kobayashi Yoshinori